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Nanostructured porous silicon scaffolds and augmented surface coatings for enhanced biocompatibility of multichannel microelectrodes
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1860/978
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| Title: | Nanostructured porous silicon scaffolds and augmented surface coatings for enhanced biocompatibility of multichannel microelectrodes |
| Authors: | Hallman, Stefanie J.
Barbee, Kenneth A.
Moxon, Karen A. |
| Keywords: | Neuroengineering |
| Issue Date: | 2006 |
| Citation: | Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Moxon_3.pdf. |
| Abstract: | Many different types of microelectrodes have been developed for use as a direct Brain-Machine Interface (BMI) to
chronically record. Unfortunately, the recordings from these microelectrode devices are not consistent and often last
for only a few weeks. The loss of these recordings is most likely due to damage to surrounding tissue that results in
the formation of non-conductive glial-scar. In conjunction with developing nanostructured electrode surfaces to
mimic the extracellular environment, we have also begun to study the effects of novel surface coatings. Preliminary
data show that Poloxamer has a positive effect on neuronal survival and is successful in decreasing the proliferation
of glial cells. |
| Description: | Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center. |
| URI: | http://hdl.handle.net/1860/978 |
| Appears in Collections: | Biomedical Technology Showcase, 2006
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