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Nanostructured porous silicon scaffolds and augmented surface coatings for enhanced biocompatibility of multichannel microelectrodes
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|Title: ||Nanostructured porous silicon scaffolds and augmented surface coatings for enhanced biocompatibility of multichannel microelectrodes|
|Authors: ||Hallman, Stefanie J.|
Barbee, Kenneth A.
Moxon, Karen A.
|Issue Date: ||2006 |
|Citation: ||Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Moxon_3.pdf.|
|Abstract: ||Many different types of microelectrodes have been developed for use as a direct Brain-Machine Interface (BMI) to
chronically record. Unfortunately, the recordings from these microelectrode devices are not consistent and often last
for only a few weeks. The loss of these recordings is most likely due to damage to surrounding tissue that results in
the formation of non-conductive glial-scar. In conjunction with developing nanostructured electrode surfaces to
mimic the extracellular environment, we have also begun to study the effects of novel surface coatings. Preliminary
data show that Poloxamer has a positive effect on neuronal survival and is successful in decreasing the proliferation
of glial cells.|
|Description: ||Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center.|
|Appears in Collections:||Biomedical Technology Showcase, 2006|
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