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Drug-loaded contrast agents for cancer tumors: a combination of imaging and therapy
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|Title: ||Drug-loaded contrast agents for cancer tumors: a combination of imaging and therapy|
|Authors: ||Burstein, Odelia Mualem|
Wheatley, Margaret A.
|Issue Date: ||2006 |
|Citation: ||Poster presented at Biomedical Technology Showcase 2006, Philadelphia, PA. Retrieved 18 Aug 2006 from http://www.biomed.drexel.edu/new04/Content/Biomed_Tech_Showcase/Poster_Presentations/Wheatley_3.pdf.|
|Abstract: ||The objective of our research is to develop methods to produce new generation ultrasound contrast agents (CA) having the added capability of serving as drug carriers. Combining imaging and drug delivery functions will enable delivery of relatively high local doses of chemotherapeutic drugs directly to tumors, triggering their release by US, thus, minimizing toxic side effects and elevating effectiveness. We investigate incorporation of Doxorubicin, a chemotherapeutic drug, into PLA (Poly-lactic acid) microcapsules, previously developed in our lab as ultrasound CA and monitor drug release methods. Effects of preparation and loading on physical (size, shape, texture) and acoustic properties were studied.|
|Description: ||Item from the Biomedical Technology Showcase held July 20, 2006 at Drexel University's Bossone Research Enterprise Center.|
|Appears in Collections:||Biomedical Technology Showcase, 2006|
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