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Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/2045

Title: A case-based framework for leveraging nutrigenomics knowledge and personal nutrition counseling
Authors: Wu, Daniel
Weber, Rosina O.
Abramson, Fredric
Issue Date: 2004
Citation: Paper presented at the 7th European Conference in Case-Based Reasoning, Madrid, Spain.
Abstract: NutriGenomics is the bioscience that links the way nutrients and other dietary components shape genetic activity. It builds on the success of Human Genome Project by applying systems biology methods to explain how the molecular components of food, supplements and pharmaceuticals dynamically influence and shape the activity of genomic subsystems, which in turn define how a person can stay healthy or become ill. Applying NutriGenomics knowledge is done through Directive Genomics, which develops purposeful dietary strategies that influence gene expression at the individual level with the goal of better genetic function and health. This paper proposes a case-based framework for leveraging nutrigenomics knowledge and Directive Genomics applications. The unique features of the proposed system include a selfmaintained distributed case base structure and a CBR-based nutrition counseling module that can learn, adapt, and maintain its case base via the integrated distributed case bases as well as external resources.
URI: http://hdl.handle.net/1860/2045
Appears in Collections:Faculty Research and Publications (IST)

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