Drexel University Home Pagewww.drexel.edu DREXEL UNIVERSITY LIBRARIES HOMEPAGE >>

iDEA: Drexel E-repository and Archives > Drexel Academic Community > College of Engineering > Department of Materials Science and Engineering > Faculty Research and Publications (MSE) > 3-mercaptopropyltrimethoxysilane as insulating coating and surface for protein immobilization for piezoelectric microcantilever sensors

Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/1657

Title: 3-mercaptopropyltrimethoxysilane as insulating coating and surface for protein immobilization for piezoelectric microcantilever sensors
Authors: Capobianco, Joseph A.
Shih, Wan Y.
Shih, Wei-Heng
Issue Date: 2007
Publisher: American Institute of Physics
Citation: Review of Scientific Instruments, 78(4): pp. 046106.
Abstract: We have examined coating PbMg1/3Nb2/3O3 0.63– PbTiO3 0.37 PMN-PT /tin and lead zirconate titanate PZT /glass piezoelectric microcantilever sensor PEMS with 3-mercaptopropyltrimethoxysilane MPS by a simple solution method to electrically insulate the PEMS for in-water applications. In contrast to earlier methytrimethoxysilane insulation coating, the MPS coating also facilitated receptor immobilization on the sensor surface via bonding of its sulhydryl group to a bifunctional linker, sulfosuccinimidyl-4- N-maleimidomethyl cyclohexane-1-carboxylate. We showed that a MPS coating of 21 nm in thickness is sufficient to electrically insulate and provide immobilization surface to the PEMS for in-liquid electrical self-excitation and self-sensing. The in-phosphate buffered saline solution resonance spectra were stable with Q values ranging from 41 to 55. The mass detection sensitivities were determined to be 5 10−11 and 8 10−12 g/Hz for the MPS-insulated PZT-glass and PMN-PT/tin PEMSs, respectively.
URI: http://dx.doi.org/10.1063/1.2727466
Appears in Collections:Faculty Research and Publications (MSE)

Files in This Item:

File Description SizeFormat
2006175084.pdf320.94 kBAdobe PDFView/Open
View Statistics

Items in iDEA are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! iDEA Software Copyright © 2002-2010  Duraspace - Feedback