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Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/1550

Title: Finite element analysis and computer aided tissue engineering design of a replacement lumbar intervertebral disc
Authors: Evans, P.J.
Sun, Wei
Issue Date: 2006
Publisher: IEEE Institute of Electrical and Electronics Engineers
Citation: Paper presented at the 2006 IEEE 32nd Annual Northeast Bioengineering Conference, Easton, PA.
Abstract: The treatment of disc degeneration disease of the spine has been a subject of particular interest in the medical community due to its effects on the lifestyle of afflicted patients. Current treatment modalities range from non-invasive treatment with physical therapy, to the invasive surgical repair of the degenerated disc(s). However, despite the existence of these treatment methods, each has its own set of drawbacks and limitations, most notably the use of surgical intervention. Examples of such limitations have included the mechanical failure of spinal implants, the destruction of the vertebral bone structure due to implant subsistence, graft site morbidity due to bone harvesting, and the promotion of disc degeneration at the surrounding spinal units. To overcome these limitations, a new implant design was conceived combining the concepts of arthrodesis, arthroplasty, and fusion via bone graft, allowing for the biological fusion of adjacent vertebra, in conjunction with the use of tissue engineering principals. In addition, this new approach to implant development, utilizing the practices of computer aided tissue engineering, permits the patient specific design of the implant, enhancing the ability to match implant design and architecture with patient anatomy. Resulting from these design criteria, the proposed novel design eliminates the drawbacks associated with the current vertebral implant designs, potentially extending both the lifespan and effectiveness of the implant, thereby improving the long term outcomes for the treatment of spinal disc degeneration.
URI: http://hdl.handle.net/1860/1550
Appears in Collections:Faculty Research and Publications (MEM)

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