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Blood coagulation and living tissue sterilization by Floating-Electrode Dielectric Barrier Discharge in air
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|Title: ||Blood coagulation and living tissue sterilization by Floating-Electrode Dielectric Barrier Discharge in air|
|Authors: ||Fridman, Gregory|
Fridman, Alexander A.
Gutsol, Alexander F.
Brooks, Ari D.
|Keywords: ||Non-Thermal Plasma;Sterilization;Disinfection;Blood Coagulation;Blood Coagulation Model;Blood Clotting;Wound Healing|
|Issue Date: ||15-Jun-2006|
|Publisher: ||Springer Verlag|
|Citation: ||Plasma Chemistry and Plasma Processing, 26(4): pp. 425-442.|
|Abstract: ||Thermal plasma discharges have been widely used in the past for treatment of
living human and animal tissue. However, extensive thermal damage and tissue desiccation
occurs due to extreme temperatures. Some solutions have been offered where the temperature
is lowered by short current pulses, addition of noble gases, or significant decrease in the size
of treatment electrodes. We propose a method of direct treatment of living tissue that occurs at
room temperature and pressure without visible or microscopic tissue damage. The presented
Floating-Electrode Dielectric Barrier Discharge plasma is proven electrically safe to human
subjects and our results show no gross (visual) or histological (microscopic) damage to skin
samples in minutes, complete tissue sterilization from skin flora in seconds, and blood clot
formation in seconds of electric plasma treatment. We also observe significant hastening of
blood clot formation via electric plasma induced catalysis of “natural” processes occurring
in human blood. A model describing these processes is offered.|
|Appears in Collections:||Faculty Research and Publications (Biomed Eng)|
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