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iDEA: Drexel E-repository and Archives > Drexel Academic Community > School of Biomedical Engineering, Science & Health Systems > Faculty Research and Publications (Biomed Eng) > Blood coagulation and living tissue sterilization by Floating-Electrode Dielectric Barrier Discharge in air

Please use this identifier to cite or link to this item: http://hdl.handle.net/1860/1148

Title: Blood coagulation and living tissue sterilization by Floating-Electrode Dielectric Barrier Discharge in air
Authors: Fridman, Gregory
Peddinghaus, Marie
Ayan, Halim
Fridman, Alexander A.
Balasubramanian, Manjula
Gutsol, Alexander F.
Brooks, Ari D.
Friedman, Gary
Keywords: Non-Thermal Plasma;Sterilization;Disinfection;Blood Coagulation;Blood Coagulation Model;Blood Clotting;Wound Healing
Issue Date: 15-Jun-2006
Publisher: Springer Verlag
Citation: Plasma Chemistry and Plasma Processing, 26(4): pp. 425-442.
Abstract: Thermal plasma discharges have been widely used in the past for treatment of living human and animal tissue. However, extensive thermal damage and tissue desiccation occurs due to extreme temperatures. Some solutions have been offered where the temperature is lowered by short current pulses, addition of noble gases, or significant decrease in the size of treatment electrodes. We propose a method of direct treatment of living tissue that occurs at room temperature and pressure without visible or microscopic tissue damage. The presented Floating-Electrode Dielectric Barrier Discharge plasma is proven electrically safe to human subjects and our results show no gross (visual) or histological (microscopic) damage to skin samples in minutes, complete tissue sterilization from skin flora in seconds, and blood clot formation in seconds of electric plasma treatment. We also observe significant hastening of blood clot formation via electric plasma induced catalysis of “natural” processes occurring in human blood. A model describing these processes is offered.
URI: http://hdl.handle.net/1860/1148
Appears in Collections:Faculty Research and Publications (Biomed Eng)

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